Friday, July 15, 2011

TOXOPLASMOSIS

nEtiology
  Toxoplasma gondii : protozoan multiply only in living cells
nToxoplasmosis infection is ubiquitonous in animal and is one of the most common latent infections of human
nHuman infection is acquired by
ØOral route via undercooked or raw meat
  Next contains cyst or by ingestion of oocyst
ØTransplacental infection from mother to fetus
nToxoplasma are not transmitted from person to person
Clinical manifestation
            vDuring vaginal/delivery
                ØAcquired toxoplasmosis
              ØCongenital toxoplasmosis

n
Diagnosis
              ØCulture : blood, body fluid, tissue speciments
                ØSerologic testing
              Elisa ( = enzym linked immunosorbent assay)
      
nTreatment
ØPolymerase chain reaction
nPrevention
Perimethamine + sulfadiazine or trisulfaperimidines
ØWomen should only eat well cooked meat
ØAvoid contact with oocyts excreted by cats
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Thursday, July 14, 2011

SCARLET FEVER (Scarlatina)

nEtiology : Group A Beta Hemolytic Streptococci
    erythrogenic toxin
nClinical manifestations
Øincubation period : 1 – 7 days
Øprodromal symptoms
vonset acute
vfever, headache, vomiting, chills
vwhite strawberry tongue
                     Øeruption :
                              vred, punctate, finely papular
                                 vblanches on pressure
                              vaxillae, groins, neck  24 hr
vred strawberry tongue
          nTreatment :
                    Øpenicillin
                    Øerythromycin
                    Øclindamycin
                    Ø1st generation cephalosporins

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VARICELLA ZOSTER VIRUS / HERPES ZOSTER / CHICKEN FOX

 nEtiology : Varicella Zoster virus (VZV)
nTransmitted in respiratory secretions and in the fluid of skin lessions
ØAirborne spread
ØDirect contact
nClinical manifestation of varicella
ØIncubation period 10 – 21 days
ØProdromal fever , malaise, anorexia, headache
ØEruption :
vScalp, face, trunk
vMacules – vesicles – crusting
vSimultaneous presence of lessions


Clinical manifestation of Herpes Zoster
Ø  Eruption in one dermatome
Treatment 
Localized pain, hyperesthesias, pruritus

nProphylaxis :
  Acyclovir : 20 mg/kg/dose
  Vaccination 
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SMALL POX By Variola / CACAR

nAcute communicable viral disease
nCharacterized by
ØPapulovesicular pustular rash
ØSevere systemic symptoms

nClinical manifestations
nEtiology : genus Orthopox virus
     -Incubation period : 12 – 14 days – 21 days
     - Prodromal symptoms
                 - Severe, abruptly 
     - Eruption : faces, lips, palms, soles
     - Papules         vesicles umbilicated multiloculus
     - 5th – 6th day      pustular      9th day     crusta
     - 3rd – 4th wk      scars

n
Complications :
   
ØPyogenic infections
ØBronchopneumonia
ØViral osteomyelitis  
ØCentral nervous systems

nTreatment
      ØNo effective specific therapy
nProphylaxis
      ØVaccination




READ MORE - SMALL POX By Variola / CACAR