TOXOPLASMOSIS

nEtiology

  Toxoplasma gondii : protozoan multiply only in living cells

nToxoplasmosis infection is ubiquitonous in animal and is one of the most common latent infections of human

nHuman infection is acquired by

ØOral route via undercooked or raw meat

  Next contains cyst or by ingestion of oocyst

ØTransplacental infection from mother to fetus

nToxoplasma are not transmitted from person to person

Clinical manifestation

            vDuring vaginal/delivery

                ØAcquired toxoplasmosis

              ØCongenital toxoplasmosis

nDiagnosis

              ØCulture : blood, body fluid, tissue speciments

                ØSerologic testing

              Elisa ( = enzym linked immunosorbent assay)

      

nTreatment

ØPolymerase chain reaction

nPrevention

Perimethamine + sulfadiazine or trisulfaperimidines

ØWomen should only eat well cooked meat

ØAvoid contact with oocyts excreted by cats